ASTM D4626-95(2019),Standard Practice for Calculation of Gas Chromatographic Response Factors.
ASTM D4626-95(2019) covers a procedure for calculating gas chromatographic response factors. It is applicable to chromatographic data obtained from a gaseous mixture or from any mixture of compounds that is normally liquid at room temperature and pressure or solids, or both, that will form a solution with liquids.
ASTM D4626-95(2019) is not intended to be applied to those compounds that react in the chromatograph or are not quantitatively eluted. Normal C6 through C11 paraffins have been chosen as model compounds for demonstration purposes.
4. Summary of practice
4. 1 Individual C6 to C11 n-paraffins are precisely weighed and combined in an inert, tight-sealing glass vial. Different concentration levels of the blend components to cover concentration ranges of interest may be obtained by dilution with a suitable solvent. As diluent, a n-paraftin, such as n-dodecane,that is, higher boiling than the blend components is suitable.
The quantitative blends are analyzed, in duplicate, by gas chromatography using either thermal conductivity, flameionization or other forms of detection. From the mass or volume composition of the blend and the raw area or peak height measurements, mass or volume response or relative response factors for each blend component are calculated.