ISO/TS 21412-2020 pdf free download.Nanotechnologies — Nano-object-assembled layers for electrochemical bio-sensing applications — Specification of characteristics and measurement methods.
This document specifies the characteristics to be measured of nano-object-assembled layers on electrodes by means of a solution process and of nano-objects constituting the layers for electrochemical applications such as nano-biosensor or diagnosis applications. It also provides measurement methods for determining the characteristics.
It does not apply to:
— the requirements of nanostructures by top-down nanomanufacturing;
— the subsequent coating of materials such as biomaterials onto nano-object-assembled layers;
— specific health and safety requirements during manufacturing;
— the experimental conditions of electrochemical sensing;
— the packaging, labelling, expiratory dates and transport of nano-object-enhanced electrochemical electrodes.
Electrochemical electrodes can exhibit nano-enhanced performance after the deposition of nano objects on the electrode surface. The increased surface area, orientation, the assembled density and ability to control the bio-receptor of the nano-object layer improves the performance of nano- iosensors, Nano-biosensor sensitivity, selectivity and reliability can be enhanced with specific nano-objects.
Currently, most of the nano-enhanced electrochemical electrodes are fabricated by researchers in order to achieve predictable performance in their own programs without mass-production. However, he technology is maturing into a commercial phase. Fabricators are offering nano-enhanced electrodes to instrument manufacturers as a platform to add additional coatings for specific sensing applications. This document supports the development of material specifications for the transaction between electrode fabrications and instrument manufacturers to allow the purchase of electrodes with predictable performance.
This document is intended to help address this issue. It is also relevant to the process of qualification, specification and use of nano-object-modified electrodes. The standardization of protocols to specify various types of nano-object-modified electrodes related to electrochemical detection will be used by most manufacturers or business owners of electrochemical electrodes products. This document focuses on the nano-object-assembled layer on electrodes by means of a solution process for electrochemical applications.
In this document, the specifications for a nano-object constituting an assembled layer are provided, based on ISO/TS 12805, which describes the characteristics of manufactured nano-objects and their measurement methods (see Annex A).In addition, the characteristics of nano-object-assembled layer for enhanced electrochemical bio-sensing applications and their measurement methods are provided in detail.