BS ISO 23905:2020,Cigarettes — Determination of selected phenolic compounds in cigarette mainstream smoke using HPLC-FLD.BS ISO 23905 pdf freed download.
BS ISO 23905 specifies a method for the quantification of selected phenolic compounds by high performance liquid chromatography with fluorescence detection (HPLC-FLD) using ISO 3308 smoking parameters. The selected phenolic compounds are: hydroquinone, resorcinol, catechol, phenol, p-Cresol, m-Cresol and o-Cresol.
BS ISO 23905 is applicable to cigarettes with total particulate matter (TPM) yields between 1 mg/cigarette and 16 mg/cigarette.
The CORESTA Smoke Analytes Sub-Group selected one method using reversed phase high performance liquid chromatography with fluorescence detection ( HPLC-FLD) for the determination of selected phenolic compounds in cigarette mainstream smoke. Smoke was collected on a glass fibre filter pad and extracted with a 1 y acetic acid solution.
A CORESTA recommended method (CRM) was writteni on the basis of the results obtained in a collaborative study conducted in 2013 involving 18 laboratories using cigarettes manufactured from a range of blend styles.
BS ISO 23905:2020 is based upon the CRM 78 and includes statistical evaluations carried out according to ISO-5725-1 and ISO 5725-2.
No machine smoking regime can represent all human smoking behaviour.
—It is recommended that cigarettes also be tested under conditions of a different intensity of machine smoking than those specified in this document.
—Machine smoking testing is useful to characterize cigarette emissions for design and regulatory urposes, but communication of machine measurements to smokers can result in misunderstandings about exposure and risk across brand.
—Smoke emission data from machine measurements may be used as inputs for product hazard assessment, but they are not intended to be nor are they valid as measures of human exposure or risks, Communicating differences between products in machine measurements as differences in exposure or risk is a misuse of testing using ISO standards.